MQLKPMEINPEMLNKVLARLGVAGQWRFVDVLGLEEETLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDLLLQDAAKVCREFTEREQGEVRFSAVALCKAA Ubiquitin thioesterase L1 UCHL1_HORSE UCHL1 Neuron cytoplasmic protein 9.5 Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity (By similarity). 223 PGP 9.5 Ubiquitin carboxyl-terminal hydrolase isozyme L1